SUTENT dosing

It’s important to remember to take SUTENT as directed by your doctor. Do not change your dose or stop taking SUTENT without first talking with your doctor.

Your doctor may change how you take SUTENT or tell you to stop taking SUTENT.

The dose of SUTENT that you are prescribed by your doctor depends on whether you have advanced renal cell carcinoma (RCC), gastrointestinal stromal tumor (GIST*), or advanced pancreatic neuroendocrine tumor (pNET). The recommended dosages for each type of cancer are below.

SUTENT comes in 12.5 mg, 25 mg, 37.5 mg, and 50 mg capsules. Your dose is taken by mouth once daily, with or without food. It's important to remember to take SUTENT as directed by your healthcare team.

Dosing Can Vary From Person to Person

Dosing can vary from person to person. It’s important to remember to take SUTENT as directed by your doctor

You may experience side effects when taking SUTENT. Tell your doctor about any changes in how you feel. If you’re having some side effects, your doctor may decide to adjust or stop your treatment. That’s why it’s important to tell your healthcare team about ANY side effects you are experiencing. You can learn about some of the potential side effects of SUTENT and also find tips to help you manage some of these side effects here.

Adjuvant Treatment Dosing
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Recommended dosage for adults with kidney cancer that has not spread (localized) and who are at high risk of renal cell carcinoma (RCC) coming back after having kidney cancer surgery

If you are prescribed SUTENT as adjuvant therapy, the recommended dose is 50 mg taken orally once a day.

  • SUTENT is taken in 6-week cycles
    • SUTENT is taken every day for the first 4 weeks (days 1 to 28) of this cycle
    • It is stopped for the next 2 weeks (days 29 to 42) to complete this cycle
    • Then the next 6-week cycle begins
    • SUTENT is taken for a total of nine 6-week cycles or as prescribed by your doctor
Advanced RCC Dosing
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Recommended dosage for advanced renal cell carcinoma (RCC)

If you are prescribed SUTENT to treat advanced RCC you may take 50 mg of SUTENT on a dosing cycle as follows:

  • SUTENT is taken once every day for 4 weeks (28 days), then it is stopped for 2 weeks (14 days). This is 1 cycle of treatment
  • This cycle is repeated for as long as your doctor tells you to
GIST Dosing
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Recommended dosage for certain patients
with GIST

If you are prescribed SUTENT to treat gastrointestinal stromal tumor (GIST) you may take 50 mg of SUTENT on a dosing cycle as follows:

  • SUTENT is taken once every day for 4 weeks (28 days), then it is stopped for 2 weeks (14 days). This is 1 cycle of treatment
  • This cycle is repeated for as long as your doctor tells you to

SUTENT is used to treat a rare cancer of the stomach, bowel, or esophagus called gastrointestinal stromal tumor (GIST) and when you have taken the medicine imatinib mesylate (Gleevec®) and it did not stop the cancer from growing or you cannot take matinib mesylate (Gleevec®). Gleevec is a registered trademark of Novartis AG.

pNET Dosing
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Recommended dosage for advanced pancreatic neuroendocrine tumor (pNET)

If you are prescribed SUTENT to treat advanced pNET, you may take 37.5 mg of SUTENT continuously, without a scheduled off-treatment period.

  • SUTENT is taken every day
  • SUTENT is taken for as long as your doctor tells you to