Angiogenesis (an-jee-o-JEN-ih-sis)
The growth of new blood vessels from existing ones. Tumors use this process to receive nutrients from the bloodstream and to metastasize.

Gastrointestinal (GASS-tro-in-TESS-tin-nul)
Relating to your stomach and intestines.

Hand-foot syndrome (hand-foot-SIN-drome)
Dryness, thickening, or cracking of the skin on the palms of the hands and soles of the feet. It can sometimes include blisters or a rash.

Hypertension (hy-per-TEN-shun)
A disease of the arteries involving constant high blood pressure.

Metastasis (muh-TAHS-tuh-sis)
The spread of cancer from one part of the body to another through the lymphatic system or bloodstream.

Proliferation (pro-liff-er-AY-shun)
When cells divide and multiply quickly. Tumors form when cancer cells proliferate.

Renal cell carcinoma (RCC) (REE-null SELL kar-sin-O-muh)
The most common form of cancer that starts in the kidneys.

Stomatitis (stow-muh-TIE-tiss)
Sores or swelling on the lining of the mouth; often a side effect of cancer therapy.

Tumor (TOO-mor)
A mass of cancer cells.

VHL
A gene that helps prevent tumor growth. If the VHL gene is not working properly, RCC can develop. VHL stands for von Hippel-Lindau.